Taizhou Zecen Biotech Co.,Ltd.
| Payment Terms | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability | 5000 Set/Sets per Month |
| Delivery Time | 15 workdays |
| Packaging Details | Carton package |
| Name | ST2 |
| Analyzer | CIA series |
| Luminescent markers | AP(alkaline phosphatase) |
| Calibration | 2-points |
| Calibrator | Free |
| Quality Control | Free |
| Storage | 2-8°C |
| Material | Magnetic beads, calibrators, Anti A/B, controls |
| Validity period | 18 months |
| Precision | ≤8% |
| Brand Name | Zecen |
| Model Number | ST2 |
| Certification | CE, ISO13485 |
| Place of Origin | China |
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Product Specification
| Payment Terms | L/C, D/A, D/P, T/T, Western Union, MoneyGram | Supply Ability | 5000 Set/Sets per Month |
| Delivery Time | 15 workdays | Packaging Details | Carton package |
| Name | ST2 | Analyzer | CIA series |
| Luminescent markers | AP(alkaline phosphatase) | Calibration | 2-points |
| Calibrator | Free | Quality Control | Free |
| Storage | 2-8°C | Material | Magnetic beads, calibrators, Anti A/B, controls |
| Validity period | 18 months | Precision | ≤8% |
| Brand Name | Zecen | Model Number | ST2 |
| Certification | CE, ISO13485 | Place of Origin | China |
| High Light | ST2 IVD Products ，CIA series IVD Products ，ST2 | ||
CLIA Reagents of Inflammation (ST2)
Description
Growth-stimulating expression gene 2 protein (ST2), a member of the interleukin-1 receptor family, has two forms: trans-model (ST2L) and soluble (sST2). The binding of ST2L to the functional ligand 1L-33 has a protective effect on the heart, and the increase of sST2 content in the blood can competitively bind to IL-33, block the 1L-33/ST2L signaling pathway, thereby inhibiting the protective effect of ST2L on the heart , the myocardial involvement, cardiac structure and function are affected, increasing the development rate of the disease.
Therefore, when heart failure occurs, the level of sST2 is significantly increased due to the mechanical stretch of the heart, thereby increasing the damage to the heart. As a new-generation marker of heart failure, ST2 has the characteristics of low biological variability, high stability, and no interference by gender, age, race, and renal function. It plays an important role in the diagnosis, treatment and risk prediction of patients with heart failure.
clinical significance
1. sST2 is mainly used for the auxiliary diagnosis of chronic heart failure, and it is of great value in its prognosis evaluation.
2. 35ng/ml is a single exclusion value, below 35ng/ml the possibility of heart failure is very small.
3. The main difference between sST2 and BNP is that it is not affected by other factors, including drugs. It can be used to evaluate whether the treatment is effective from the perspective of indicators, and it can also be used as a readmission risk assessment.
Analysis of results
If the sST2 content of the sample is lower than 35ng/mL, it is regarded as normal;
If it is higher than 35ng/mL, it suggests that the patient may suffer from heart failure.
| Test Item | ST2 |
| Luminescent Principle | Enzymatic chemiluminescence |
| Luminescent Markers | AP(alkaline phosphatase) |
| Specification | 100 Test/Kit for CIA series |
| / | |
| Principle | Sandwich method |
| Component | Magnetic Beads |
| Calibrator Low | |
| Calibrator High | |
| Anti-A/Anti-B | |
| Control 1 | |
| Control 2 | |
| Accessories Required But Not Provided | Substrate |
| Washing solution | |
| Sample material | Serum |
| Storage | 2-8℃ |
Company Details
Business Type:
Manufacturer
Year Established:
2011
Employee Number:
300~500
Ecer Certification：
Active Member
Zecen Biotech CO., LTD., founded in 2011, is a leading Chinese diagnostics manufacturer specializing in in-vitro diagnostics devices and reagents. Zecen focus on the Chemiluminescent immunoassay (CLIA) field. With all products CE marked, our market presence currently spreads from across China to oth... Zecen Biotech CO., LTD., founded in 2011, is a leading Chinese diagnostics manufacturer specializing in in-vitro diagnostics devices and reagents. Zecen focus on the Chemiluminescent immunoassay (CLIA) field. With all products CE marked, our market presence currently spreads from across China to oth...
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